Weida Hu, Casey Papovich, Lu Shen, Pablo Arrabal Haro, Bren E. Backhaus, Nikko J. Cleri, Mark Dickinson, James S. Dunlop, Steven L. Finkelstein, Mauro Giavalisco, Anton M. Koekemoer, Vasily Kokorev, Sara Mascia, Lorenzo Napolitano, Laura Pentericci, Aaron Smith, Anthony J. Taylor, Xin Wang, L. Y. Aaron Yung

We present a study of intergalactic medium (IGM) transmission at $4.5 < z < 6.5$ using high-signal-to-noise JWST/NIRSpec prism spectroscopy of 143 galaxies at $5<z<7$ from the CAPERS and JADES surveys. By comparing the observed flux blueward of Ly$α$ emission line to the prediction of spectral energy distribution modeling, we directly measure the IGM transmission along the individual galaxy sightlines. The average transmission measured from these galaxy sightlines is consistent with previous measurements based on luminous quasars. Current NIRSpec spectroscopy is sufficiently deep to probe IGM transmission on single sightlines. We find evidence for a highly ionized structure, \bubble, at $z\sim 5.75-6$ in the GOODS-S field based on the analysis of a high-S/N spectrum of one galaxy, GS-18846, at $z=6.335$. The IGM transmission of GS-z6IS is $0.17\pm0.02$, an order of magnitude higher than the average of previous measurements at this redshift. This structure has a line-of-sight scale of $\sim110$ cMpc and spatially extends over at least $21\times17$ cMpc$^2$. GS-z6IS is associated with a known large-scale galaxy overdensity at the same redshift, whose member galaxies show enhanced Ly$α$ visibility and a broader Ly$α$ equivalent width distribution compared to field galaxies at similar redshift. This result supports the interpretation that Ly$α$ overdensity can trace bubbles of increased IGM transmission, although environmental effects on galaxy properties may also contribute. Our study demonstrates that high-S/N galaxy spectra offer a powerful new approach to tracing ionized structures during the epoch of reionization.