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Computational Design and Atomistic Validation of a High-Affinity VHH Nanobody Targeting the PI/RuvC Interface of Streptococcus pyogenes Cas9: A Bivalent Hub Strategy for CRISPR-Cas9 Enhancement

Computational Design and Atomistic Validation ...

Bioinformatics
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AI-guided design of candidate BMPR1A-binding peptides for cartilage regeneration: a multi-tool computational benchmarking study

AI-guided design of candidate BMPR1A-binding p...

Bioinformatics
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librarian
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Virtual absorption modes of Schwarzschild-de Sitter spacetimes in semi-open systems

Virtual absorption modes of Schwarzschild-de S...

General Relativity and Quantum Cosmology
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Liang-Bi Wu
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Identification of two genomic cryptotypes of Plasmodium malariae in Africa

Identification of two genomic cryptotypes of P...

Genomics
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Margaux Lefebvre
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Investigating peculiar prompt emission properties of the multi-Peaked GRB 250129A

Investigating peculiar prompt emission propert...

High Energy Astrophysical Phenomena
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Spatio-temporal shifts driven by climate change threaten persistence and resilience of honey bee populations

Spatio-temporal shifts driven by climate chang...

Ecology
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Structural Insights into Bromodomain-Containing Complexes from Trypanosoma cruzi Revealed by Proximity Labeling and Stoichiometric Space Exploration

Structural Insights into Bromodomain-Containin...

Molecular Biology
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Elvio Rodríguez Araya
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Beyond Regional Activations: Structural Connectivity Message-Passing Shallow Neural Networks for Brain Decoding

Beyond Regional Activations: Structural Connec...

Neuroscience
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Specific targeting of MR1-antigen complexes using nanobodies

Specific targeting of MR1-antigen complexes us...

Immunology
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Nicholas Gherardin
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Transporter-Mediated Uptake of Microcystin-LR in Human Trophoblasts: Regulation By Oxygen Concentration and Cell Fusion

Transporter-Mediated Uptake of Microcystin-LR ...

Pharmacology and Toxicology
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In vitro investigation and evaluation of the antidiabetic potential of the ethanolic extract of Asparagus racemosus using starch digestion, glucose diffusion, glucose uptake, and DPPH assays

In vitro investigation and evaluation of the a...

Pharmacology and Toxicology
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Md. Sifat Rahman
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Barcoding biology: Chemotype predicts variation in genotype, physiology, and stress response

Barcoding biology: Chemotype predicts variatio...

Systems Biology
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Depletion and replacement of tissue resident macrophages in mice with germ-line deletion of a conserved enhancer in the Csf1r locus.

Depletion and replacement of tissue resident m...

Immunology
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Turning the knobs on dust evolution: Comparing codes, parameters and their effects on planet formation and disc observables

Turning the knobs on dust evolution: Comparing...

Earth and Planetary Astrophysics
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librarian
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Ovary-Derived Signals Align Protein Appetite with Oogenesis

Ovary-Derived Signals Align Protein Appetite w...

Physiology
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Zita Santos
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Cluster Infall for Mass Calibration in the Stage-IV Era

Cluster Infall for Mass Calibration in the Sta...

Cosmology and Nongalactic Astrophysics
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Connor Sweeney
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Spontaneous scalarization of neutron stars in teleparallel gravity with derivative torsional coupling

Spontaneous scalarization of neutron stars in ...

General Relativity and Quantum Cosmology
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librarian
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Photometric and late-time spectropolarimetric observations of GRB 250129A afterglow

Photometric and late-time spectropolarimetric ...

High Energy Astrophysical Phenomena
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librarian
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Semi-cosmographic constraints on decaying dark matter and dynamical dark energy: DESI DR2 BAO and 21\, cm intensity-mapping forecasts

Semi-cosmographic constraints on decaying dark...

Cosmology and Nongalactic Astrophysics
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Mohit Yadav
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Identification of low redshift groups and clusters of galaxies in the X-CLASS survey and the X-ray luminosity-temperature relation

Identification of low redshift groups and clus...

Cosmology and Nongalactic Astrophysics
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Quentin Moysan
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Inflation driven by a bare cosmological constant and its graceful exit

Inflation driven by a bare cosmological consta...

General Relativity and Quantum Cosmology
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Shuxun Tian
2 views
How Massive Can a Population III Starburst Be? Simulating the First Galaxies with High Lyman-Werner Background

How Massive Can a Population III Starburst Be?...

Astrophysics of Galaxies
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Tae Bong Jeong
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The Radio-wave Observations at the Lunar Surface of the photoElectron Sheath (ROLSES) instrument onboard the Intuitive Machines-1 Mission to the Moon

The Radio-wave Observations at the Lunar Surfa...

Instrumentation and Methods for Astrophysics
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Nat Gopalswamy
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Neonatal regulatory T cells promote alveologenesis by restraining neutrophil-mediated inflammation

Neonatal regulatory T cells promote alveologen...

Immunology
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Primordial Non-Gaussianity and the Field-Level Cramer-Rao Bound

Primordial Non-Gaussianity and the Field-Level...

Cosmology and Nongalactic Astrophysics
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2 views
Virulence studies of the human gut pathobiont Bilophila wadsworthia using Galleria mellonella as model host

Virulence studies of the human gut pathobiont ...

Microbiology
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librarian
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Population Structure and Antimicrobial Resistance Gene Transfer of Respiratory Escherichia coli Isolated from Swine in China

Population Structure and Antimicrobial Resista...

Microbiology
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Junlong Zhao
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Both ATP and Mg2+ are Required for High-Affinity Binding of Indolmycin to Human Mitochondrial Tryptophanyl-tRNA Synthetase

Both ATP and Mg2+ are Required for High-Affini...

Biophysics
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Visual Function Correlates More Strongly with Glial Coverage than Axon Count Across Multiple Mouse Strains

Visual Function Correlates More Strongly with ...

Neuroscience
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librarian
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MAGIC observations of NGC 4278. The first low-luminosity radio galaxy with compact jets detected at TeV energies

MAGIC observations of NGC 4278. The first low-...

High Energy Astrophysical Phenomena
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librarian
3 views
Modulating Innate Immune Responses to Curli Fibers Through Protein Engineering

Modulating Innate Immune Responses to Curli Fi...

Synthetic Biology
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Neel Joshi
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3D NLTE Sodium abundances in late-type stars. Abundance corrections and synthetic spectra

3D NLTE Sodium abundances in late-type stars. ...

Solar and Stellar Astrophysics
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Gloria Canocchi
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