Bioinformatics

SteerAF: Distogram-based Steering of AlphaFold2 toward Alternative Conformations

SteerAF: Distogram-based Steering of AlphaFold...

Bioinformatics
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librarian
2 views
OmniPath Metabo: chemical structures, interactions and mechanisms to study the metabolome

OmniPath Metabo: chemical structures, interact...

Bioinformatics
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librarian
2 views
Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY Analogs

Structure Bioinformatics of Eight Human ATP Sy...

Bioinformatics
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librarian
2 views
Structure-Based Immunoinformatics Design of a CTB-Adjuvanted Multi-Epitope Mucosal Vaccine Against Helicobacter pylori

Structure-Based Immunoinformatics Design of a ...

Bioinformatics
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Razieh Veisi
2 views
Predicting optimal growth temperatures of bacteria using learned structural information from a single protein

Predicting optimal growth temperatures of bact...

Bioinformatics
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Michael Hoffert
3 views
MorphoStat: A Statistics-Aware Pipeline for Morphological Profiling Analysis

MorphoStat: A Statistics-Aware Pipeline for Mo...

Bioinformatics
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librarian
4 views
Looking beyond stereotyped neuron structures reveals links between beading and morphological rearrangements in aging phenotypes.

Looking beyond stereotyped neuron structures r...

Bioinformatics
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Adriana San Miguel
5 views
Accounting for allelic diversity and multicopy gene detection improves the accuracy of antibiotic resistance genotypic determination

Accounting for allelic diversity and multicopy...

Bioinformatics
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Francesc Coll
6 views
Integrating Histology with Spatial Molecular Programs Using a Multimodal Foundation Model

Integrating Histology with Spatial Molecular P...

Bioinformatics
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Zongxu Zhang
49 views
Distinct fibrotic, epithelial and immune transcriptomic programs in phenotypes of chronic lung allograft dysfunction

Distinct fibrotic, epithelial and immune trans...

Bioinformatics
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craig-thorburn
56 views
CANCAN: high-resolution copy number and mutation heterogeneity analysis of DNA sequence data for clinical applications

CANCAN: high-resolution copy number and mutati...

Bioinformatics
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librarian
88 views
ToxCastLite: A portable semantic evidence graph linking in vitro bioactivity, in vivo toxicity, and exposure-use context

ToxCastLite: A portable semantic evidence grap...

Bioinformatics
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librarian
95 views
PocketBagger: Generalizable pocket druggability prediction via positive-unlabeled learning

PocketBagger: Generalizable pocket druggabilit...

Bioinformatics
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librarian
87 views
Multi-Scale Tri-Modal Histology Dataset Integrating Tumor Morphology, Immune Patterns, and Clinical Outcomes

Multi-Scale Tri-Modal Histology Dataset Integr...

Bioinformatics
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librarian
110 views
HESTIA: Scalable Multimodal Integration of Histology and High-Resolution Spatial Transcriptomics for Robust Spatial Domain Identification

HESTIA: Scalable Multimodal Integration of His...

Bioinformatics
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librarian
69 views
Interpretable Predictive Modeling for Medical Data Using Boolean Rule-aware Regression

Interpretable Predictive Modeling for Medical ...

Bioinformatics
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librarian
84 views
Elab2ARC: A Browser-Based Workspace for Converting Free-Text Protocols into rich FAIR digital objects

Elab2ARC: A Browser-Based Workspace for Conver...

Bioinformatics
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Sabrina Zander
96 views
A unified benchmark of synthetic data generation for clinical transcriptomic cancer cohorts

A unified benchmark of synthetic data generati...

Bioinformatics
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Christophe BATTAIL
86 views
Identifying Treatment Related Signatures In Glioblastoma Using KaleidoCell

Identifying Treatment Related Signatures In Gl...

Bioinformatics
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Jean Radig
93 views
Biological foundation models illuminate annotation blind spots in evolutionarily divergent genomes

Biological foundation models illuminate annota...

Bioinformatics
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librarian
83 views
TransXplorer: An automated translational discovery platform for RNA-seq data

TransXplorer: An automated translational disco...

Bioinformatics
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Varinder Madhav Verma
98 views
The human gut virome is a non-redundant and clinically informative component of the microbiome

The human gut virome is a non-redundant and cl...

Bioinformatics
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librarian
78 views
A modular Bayesian framework for inferring transmission networks from polyclonal infections, with application to Plasmodium falciparum

A modular Bayesian framework for inferring tra...

Bioinformatics
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librarian
88 views
Pan-Viral Conformational Landscapes of Frameshifting Elements Reveal Length-Dependent Plasticity and Antisense-Driven Structural Reprogramming

Pan-Viral Conformational Landscapes of Framesh...

Bioinformatics
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librarian
82 views
Deep learning models for chemical perturbation prediction do not yet utilise drug molecular features

Deep learning models for chemical perturbation...

Bioinformatics
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librarian
97 views
Metabolic Self-Organization: Emergence of Autonomous Agency in a Metabolically Constrained LLMs

Metabolic Self-Organization: Emergence of Auto...

Bioinformatics
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librarian
84 views
Physics-Informed Neural Networks for Parameter Recovery in the Repressilator Oscillatory Model

Physics-Informed Neural Networks for Parameter...

Bioinformatics
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Jordi Villà-Freixa
99 views
Exploring the Mechanism of Na⁺/K⁺-ATPase (NKA) and 20-HETE Ligand Interactions by in-silico modeling

Exploring the Mechanism of Na⁺/K⁺-ATPase (NKA)...

Bioinformatics
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librarian
78 views
TDP-43 regulates chromatin looping and gene transcription through binding and stabilizing DNA G-quadruplex structures

TDP-43 regulates chromatin looping and gene tr...

Bioinformatics
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librarian
84 views
Machine learning-based Personalized Dietary Recommendations to Achieve Desired Gut Microbial Compositions

Machine learning-based Personalized Dietary Re...

Bioinformatics
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librarian
88 views
Improving Variant Effect Prediction by Steering Sparse Mechanistic Features in Protein Language Models

Improving Variant Effect Prediction by Steerin...

Bioinformatics
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Yonghong He
86 views
DeSpotX: Identifiability-Based Decontamination for Spatial Transcriptomics

DeSpotX: Identifiability-Based Decontamination...

Bioinformatics
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librarian
85 views
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