Cancer Biology

Development and design rules for a modular human peptide-tag adaptor CAR T cell system

Development and design rules for a modular hum...

Cancer Biology
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Ziduo Li
140 views
Ascorbate is a physiological tumor suppressor metabolite in leukemia

Ascorbate is a physiological tumor suppressor ...

Cancer Biology
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Michalis Agathocleous
55 views
Temporal Dynamics of SMARCA4 Loss Define Its Role in Myogenic Differentiation of Alveolar Rhabdomyosarcoma

Temporal Dynamics of SMARCA4 Loss Define Its R...

Cancer Biology
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librarian
55 views
Inflammation is an essential trigger for POLE-driven ultramutated colorectal cancer

Inflammation is an essential trigger for POLE-...

Cancer Biology
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librarian
49 views
Tobacco Carcinogen Induces Persistent DNA Damage and Homologous Recombination Dysregulation in Pancreatic Ductal Carcinogenesis

Tobacco Carcinogen Induces Persistent DNA Dama...

Cancer Biology
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librarian
67 views
A microbiota-driven neuroepithelial feed-forward circuit drives gastroesophageal junction tumorigenesis

A microbiota-driven neuroepithelial feed-forwa...

Cancer Biology
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librarian
74 views
Preoperative thymic output and T cell repertoire diversity are associated with recurrence after nephrectomy for localized renal cell carcinoma

Preoperative thymic output and T cell repertoi...

Cancer Biology
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Iben Lyskjær
56 views
A Multi-Kinase Inhibitor Screen Identifies mTOR Signaling as a Vulnerability in Advanced Prostate Cancer.

A Multi-Kinase Inhibitor Screen Identifies mTO...

Cancer Biology
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librarian
66 views
p53 activity links chromosomal instability to pro-migratory extracellular vesicles

p53 activity links chromosomal instability to ...

Cancer Biology
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librarian
73 views
p53 restoration suppresses retrotransposon-driven chromosomal instability through nonlinear let-7 feedback and stochastic burst control

p53 restoration suppresses retrotransposon-dri...

Cancer Biology
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L. Boominathan
188 views
Ovarian cancer-on-chip for patient-specific profiling of treatment responses to sequential chemotherapy and PD-L1 blockade

Ovarian cancer-on-chip for patient-specific pr...

Cancer Biology
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librarian
285 views
A transcriptional signature of LKB1 functional loss defines a large, therapeutically addressable patient population across human cancers

A transcriptional signature of LKB1 functional...

Cancer Biology
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librarian
202 views
Intratumoral dose heterogeneity promotes adaptive anti-tumor immunity and predicts clinical response to radiopharmaceutical therapy

Intratumoral dose heterogeneity promotes adapt...

Cancer Biology
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librarian
200 views
Routine FFPE sections support clinically compatible single-nucleus transcriptomics across six human cancer types

Routine FFPE sections support clinically compa...

Cancer Biology
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librarian
197 views
A dual-layer computational framework for prioritising therapeutic candidates targeting extracellular vesicle-mediated immune escape in pancreatic ductal adenocarcinoma

A dual-layer computational framework for prior...

Cancer Biology
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Xiaoying Zhang
214 views
Pulsed priming with the FAK inhibitor narmafotinib enhances both gemcitabine/Abraxane and FOLFIRINOX chemotherapy response in pancreatic cancer

Pulsed priming with the FAK inhibitor narmafot...

Cancer Biology
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Paul Timpson
220 views
Macrophage-instructed GSDME couples glioblastoma cell-state plasticity with inflammatory cell death

Macrophage-instructed GSDME couples glioblasto...

Cancer Biology
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librarian
234 views
An Integrated Preclinical Platform for Lethal Neuroendocrine Prostate Cancer from Rapid Autopsy Bone and Liver Metastases.

An Integrated Preclinical Platform for Lethal ...

Cancer Biology
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Grinu Mathew
216 views
An immune-stimulating antibody conjugate spatiotemporally targeting CD47 and TLR9 elicits macrophage-dependent tumor clearance and durable anti-cancer adaptive immunity

An immune-stimulating antibody conjugate spati...

Cancer Biology
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Jung Suk
220 views
Genetic and Pharmacologic Targeting of Eya3 in Macrophages Drives Anti-Tumor Immunity in Triple-Negative Breast Cancer

Genetic and Pharmacologic Targeting of Eya3 in...

Cancer Biology
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librarian
229 views
A Novel Syngeneic Mouse Model to Study Immune Evasion in Head and Neck Squamous Cell Carcinoma

A Novel Syngeneic Mouse Model to Study Immune ...

Cancer Biology
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librarian
218 views
Ribonucleotide Reductase Inhibition Overcomes FLT3 Inhibitor Resistance in Acute Myeloid Leukemia

Ribonucleotide Reductase Inhibition Overcomes ...

Cancer Biology
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librarian
217 views
Circulating Immune Profiling Reveals Immune Signatures Associated with Disease Stage and Outcome in Endometrial Cancer

Circulating Immune Profiling Reveals Immune Si...

Cancer Biology
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librarian
198 views
iPSC-Derived Microglia-like Cells Exhibit Protocol-Dependent Transcriptomic Features and Robust Phagocytosis of Glioma Cells

iPSC-Derived Microglia-like Cells Exhibit Prot...

Cancer Biology
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librarian
203 views
Topical Activatable Fluorescence Probes for Rapid Intraoperative Detection of Peritoneal Dissemination in High-Grade Serous Ovarian Carcinoma

Topical Activatable Fluorescence Probes for Ra...

Cancer Biology
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librarian
208 views
Whole transcriptome analysis reveals ELK3 as a key driver of metastasis through regulation of 3D migration and stemness in triple-negative breast cancer cells

Whole transcriptome analysis reveals ELK3 as a...

Cancer Biology
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Daniel Cruceriu
211 views
IL-32 is a stress-responsive node locked in a noncanonical NF-κB inflammatory loop during MASLD to HCC transition

IL-32 is a stress-responsive node locked in a ...

Cancer Biology
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Jesper Andersen
231 views
Enterococcus faecalis is involved in the progression of the early stages of latent chronic pancreatitis surrounding pancreatic cancer tissue

Enterococcus faecalis is involved in the progr...

Cancer Biology
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librarian
215 views
Distinct Effects of the Extracellular Matrix on Tumor Organization and Response to Cancer Virotherapy

Distinct Effects of the Extracellular Matrix o...

Cancer Biology
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librarian
223 views
Mapping Functional Tumor Suppressor Networks in Esophageal Adenocarcinoma Using In Vivo CRISPR Screening and Perturb-sequencing

Mapping Functional Tumor Suppressor Networks i...

Cancer Biology
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Nicholas Clemons
218 views
A Pan-Cancer Multi-Omic Analysis of Copy Number Signature Clusters and Genomic Instability

A Pan-Cancer Multi-Omic Analysis of Copy Numbe...

Cancer Biology
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librarian
219 views
Chemokine-Dependent Natural Killer Cells Prevent Pulmonary Metastasis in a Newly Established Mouse Osteosarcoma Model

Chemokine-Dependent Natural Killer Cells Preve...

Cancer Biology
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librarian
218 views
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