Immunology

Rational Generation of Monoclonal Antibodies and Intrabodies Selective for Pathogenic TDP-43

Rational Generation of Monoclonal Antibodies a...

Immunology
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librarian
33 views
Mitochondrial Bioenergetic Failure in SLE Immunocytes: Targeting Fitness for Therapy

Mitochondrial Bioenergetic Failure in SLE Immu...

Immunology
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librarian
31 views
Accumulation of SA-βGal High Cells in Human Naive T Cell Compartments Reveals a Stress-Adapted, Senescent-Like State

Accumulation of SA-βGal High Cells in Human Na...

Immunology
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librarian
27 views
A single MHCII neoepitope mRNA vaccine elicits CD4 T- and B- cell responses promoting endogenous CD8 anti-tumor immunity

A single MHCII neoepitope mRNA vaccine elicits...

Immunology
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Aude-Hélène Capietto
62 views
Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis

Depletion of extracellular asparagine impairs ...

Immunology
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librarian
54 views
Selective targeting of IL-1RAP-dependent eosinophilic inflammation in allergic fungal airway disease

Selective targeting of IL-1RAP-dependent eosin...

Immunology
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librarian
57 views
Measles vaccine attenuation comprises innate immune cell infection and interferon responses

Measles vaccine attenuation comprises innate i...

Immunology
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Christian Pfaller
58 views
ALOX12B overexpression in the skin drives inflammasome/Th17 signaling axis to promote inflammation in the mouse model and human patients

ALOX12B overexpression in the skin drives infl...

Immunology
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Nooruddin Khan
55 views
DEVELOPMENT OF A POTENT MONOCLONAL ANTIBODY FOR TREATMENT OF HUMAN METAPNEUMOVIRUS INFECTIONS

DEVELOPMENT OF A POTENT MONOCLONAL ANTIBODY FO...

Immunology
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Jim Boonyaratanakornkit
79 views
How Ikaros and Aiolos homo- and heterodimers drive gene expression to ensure B cell development

How Ikaros and Aiolos homo- and heterodimers d...

Immunology
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Susan Chan
61 views
Dendritic cell-intrinsic TLR/MyD88 signaling promotes the clearance of a live-attenuated oral vaccine

Dendritic cell-intrinsic TLR/MyD88 signaling p...

Immunology
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Guangming Zhong
58 views
Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism.

Kmo restricts Salmonella in a whole organism i...

Immunology
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librarian
57 views
Impact of serum versus anticoagulant-containing plasma on influenza virusneuraminidase-based serological assays

Impact of serum versus anticoagulant-containin...

Immunology
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librarian
56 views
Loss of B cell tolerance at the T2/T3a B cell transition is a convergent pathogenic mechanism in common variable immunodeficiency

Loss of B cell tolerance at the T2/T3a B cell ...

Immunology
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Jocelyn Farmer
59 views
Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T cell-mediated cytotoxicity

Maintenance of chronic neuroinflammation in mu...

Immunology
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librarian
69 views
The immune landscape of pediatric Brain and Solid Tumors: A systematic review and integration of immunohistochemistry and single-cell RNA sequencing data

The immune landscape of pediatric Brain and So...

Immunology
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librarian
69 views
Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

Acute anaphylactic and multiorgan inflammatory...

Immunology
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librarian
71 views
Zα domain-dependent ZBP1 condensate formation induces an amyloidal necroptotic signalling complex

Zα domain-dependent ZBP1 condensate formation ...

Immunology
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librarian
75 views
Inflammasome activation differences underpin different Mycobacterium tuberculosis infection outcomes

Inflammasome activation differences underpin d...

Immunology
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librarian
79 views
Imaging CRISPR-Edited CAR-T Cell Therapies with Optical and Positron Emission Tomography Reporters

Imaging CRISPR-Edited CAR-T Cell Therapies wit...

Immunology
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librarian
74 views
Persistent ECM Scarring Reprograms Intestinal Stem Cells to Drive Chronic Inflammation

Persistent ECM Scarring Reprograms Intestinal ...

Immunology
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librarian
80 views
TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950

TH5487 specifically targets NLRP3 in FCAS pati...

Immunology
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librarian
80 views
Interlinked roles for HEB and Id3 in fetal gamma-delta T cell commitment and functional programming

Interlinked roles for HEB and Id3 in fetal gam...

Immunology
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librarian
82 views
CFTR mutation leads to intrinsic dysfunction in neutrophils from people with Cystic Fibrosis

CFTR mutation leads to intrinsic dysfunction i...

Immunology
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Santiago PartidaSanchez
77 views
Duration of immunity following infection with moderately virulent ASFV

Duration of immunity following infection with ...

Immunology
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librarian
80 views
Rational Design of Immunogenic Nanoparticles as a Platform for Enhanced Ovarian Cancer Immunotherapy in Mice

Rational Design of Immunogenic Nanoparticles a...

Immunology
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librarian
79 views
Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye

Clusterin reverses epitheliopathy, reduces inf...

Immunology
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librarian
78 views
Unheralded high MHC Class II polymorphism in the abundant Atlantic herring resolved by long-read sequencing

Unheralded high MHC Class II polymorphism in t...

Immunology
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librarian
80 views
Transcriptome-Proteome analysis of human naive and memory B cell subsets reveal isotype and subclass-specific phenotypes

Transcriptome-Proteome analysis of human naive...

Immunology
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librarian
81 views
Single-cell and cell-type-level insights into stress-driven immune regulation relevant to disease

Single-cell and cell-type-level insights into ...

Immunology
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Anthony Zannas
92 views
KDM5A enhances MHC-I antigen presentation and potentiates antitumor immunity unleashed by immune checkpoint blockade

KDM5A enhances MHC-I antigen presentation and ...

Immunology
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librarian
85 views
Locust cGAS-like receptors recognize derivatives of a Gypsy retrotransposon to synergize with RNAi against viral invasion

Locust cGAS-like receptors recognize derivativ...

Immunology
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He-Ying Qian
83 views
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