Molecular Biology

Negative epistasis limits current codon optimization approaches

Negative epistasis limits current codon optimi...

Molecular Biology
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Zrinka Raguz Nakic
3 views
Uncovering Host-Parasite Dynamics: Gene Expression Shifts in Hematodinium-infected Chionoecetes bairdi in Response to Temperature ChangeChanges in gene expression under differing temperature regimes of infected Chionoecetes bairdi and the parasitic dinoflagellate Hematodinium sp.

Uncovering Host-Parasite Dynamics: Gene Expres...

Molecular Biology
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librarian
4 views
IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2V617F clonal hematopoiesis-driven atherosclerosis.

IL-18 inhibition enlarges lesions, necrotic co...

Molecular Biology
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Mojdeh Tavallaie
5 views
Dynamic DnaA-DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication

Dynamic DnaA-DnaB interactions at oriC coordin...

Molecular Biology
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Tsutomu Katayama
7 views
Designing a broad-spectrum four-helix bundle targeting different strains of SARS-CoV-2 Spike Receptor Binding Domains with ACE2-like binding interface

Designing a broad-spectrum four-helix bundle t...

Molecular Biology
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librarian
6 views
The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome

The longevity effects of reduced IGF-1 signali...

Molecular Biology
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librarian
6 views
SOX2 and SOX9 as Transcriptional Regulators of human Galectin-3 in SW1353 Cells: Potential Implications for Osteoarthritis

SOX2 and SOX9 as Transcriptional Regulators of...

Molecular Biology
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librarian
21 views
Dcaf17 knockdown integrates mitochondrial-lysosomal dysfunction with ferroptosis, NLRP3 inflammasome signaling and necroptosis

Dcaf17 knockdown integrates mitochondrial-lyso...

Molecular Biology
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librarian
18 views
Mechanobiological proximal tubular defects in ARC syndrome: A VPS33B CRISPR knockout study

Mechanobiological proximal tubular defects in ...

Molecular Biology
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librarian
13 views
Structural insights into context-specific inhibition of bacterial translation by macrolides

Structural insights into context-specific inhi...

Molecular Biology
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librarian
14 views
The endoribonuclease Rae1 from Bacillus subtilis cleaves mRNA upstream of stalled ribosomes

The endoribonuclease Rae1 from Bacillus subtil...

Molecular Biology
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librarian
13 views
DiffDock-Glide: a hybrid physics-based and data-driven approach to molecular docking

DiffDock-Glide: a hybrid physics-based and dat...

Molecular Biology
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Steven Jerome
13 views
Cytokine expression profile in the human brain of older adults

Cytokine expression profile in the human brain...

Molecular Biology
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Katia Lopes
17 views
Translation-specific disruption of Col1a1 expression in multiple models of Spinal Muscular Atrophy can be rescued by Risdiplam.

Translation-specific disruption of Col1a1 expr...

Molecular Biology
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Gabriella Viero
20 views
Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells

Single cell multiomic analysis of the impact o...

Molecular Biology
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librarian
17 views
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids

Structural basis of liver de-targeting and neu...

Molecular Biology
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Seongmin Jang
22 views
A minimal hybridization capture system for the parallel enrichment and cost-effective detection of ancient human pathogens

A minimal hybridization capture system for the...

Molecular Biology
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librarian
29 views
Genetic response to light and carbon source variations in Trichoderma harzianum: The key regulatory roles of env1, cre1, and blr2

Genetic response to light and carbon source va...

Molecular Biology
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librarian
29 views
SR9009 Regulates Macrophage Polarization via the NR1D1/NF-κB Axis to Ameliorate Obesity Associated Ulcerative Colitis

SR9009 Regulates Macrophage Polarization via t...

Molecular Biology
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Zhi Xue Zheng
38 views
Development of a CRISPR/Cas9-induced gene editing system for Pseudoalteromona fuliginea and its applications in functional genomics

Development of a CRISPR/Cas9-induced gene edit...

Molecular Biology
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librarian
35 views
A Catalytically Inactive Protein Kinase C alpha Mutation Drives Chordoid Glioma by Pathway Rewiring

A Catalytically Inactive Protein Kinase C alph...

Molecular Biology
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librarian
35 views
Affinity-selected peptide ligands specifically bind i-motif DNA and modulate c-Myc gene expression

Affinity-selected peptide ligands specifically...

Molecular Biology
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librarian
36 views
PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling

PTP1B inhibition promotes microglial phagocyto...

Molecular Biology
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Nicholas Tonks
37 views
HCR-Proxy resolves site-specific proximal RNA proteomes at subcompartmental nanoscale resolution

HCR-Proxy resolves site-specific proximal RNA ...

Molecular Biology
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librarian
35 views
Therapeutic antisense oligonucleotide mitigates retinal dysfunction in a pig model of CLN3 Batten disease

Therapeutic antisense oligonucleotide mitigate...

Molecular Biology
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librarian
35 views
Anellovirus protein coded by ORF2/3 recruits host cell replication andhomologous recombination machinery during replication

Anellovirus protein coded by ORF2/3 recruits h...

Molecular Biology
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librarian
36 views
Inhibition of p38 MAPK after repetitive mild TBI ameliorates immune signaling and behavioral deficits

Inhibition of p38 MAPK after repetitive mild T...

Molecular Biology
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librarian
37 views
BRD4 binds the nucleosome via both histone and DNA interactions

BRD4 binds the nucleosome via both histone and...

Molecular Biology
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Jiang Zhu
38 views
Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8

Control of retrotransposon-driven activation o...

Molecular Biology
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librarian
37 views
Automated SP3 Workflow Enables Robust Sample Preparation on Proteonano Ultraplex Proteomics Platform

Automated SP3 Workflow Enables Robust Sample P...

Molecular Biology
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librarian
34 views
Transcriptomic perspective on acromegaly-related PIT-1/SF-1 positive pituitary tumors

Transcriptomic perspective on acromegaly-relat...

Molecular Biology
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Julia Rymuza
34 views
Co-transcriptional folding orchestrates sequential multi-effector sensing by a glycine tandem riboswitch

Co-transcriptional folding orchestrates sequen...

Molecular Biology
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librarian
34 views
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