Synthetic Biology

Tuning viscoelasticity and fine structure of living materials via synthetic adhesion logic and rheological perturbations
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librarian
14 views
Cell-free genome-wide transcriptomics through machine learning optimization
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librarian
14 views
DNA framework array enables ultra-high throughput DNA synthesis
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librarian
37 views
Unified Genomic and Chemical Representations Enable Bidirectional Bio-synthetic Gene Cluster and Natural Product Retrieval
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Chuan Sheng Foo
37 views
Carbon-Efficient Conversion through Hydrogen and Formate-Driven Metabolism in Escherichia coli
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Jay Keasling
37 views
DNA Flipping as Facile Mechanism for Transmembrane Signaling in Synthetic Cells
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Lorena Pellejero
40 views
Changing the initiation unit of nonribosomal peptide synthetases to access underexplored biosynthetic potential
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Xiaoying Bian
41 views
De novo design of hundreds of functional GPCR-targeting antibodies enabled by scaling test-time compute
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librarian
40 views
Making deep mutational scanning accessible: a cost-efficient approach to construct barcoded libraries for genes of any length
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librarian
42 views
Characterization of recombinase-based genetic parts and circuits using nanopore sequencing
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librarian
41 views
Using domain insertion to create sulfite reductases that present chemical-dependent activities
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librarian
41 views
Orchestrating Self-Replication in Artificial Cells through Digital Microfluidics
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Mark Wallace
41 views
When good guides go bad: empirical evaluation of all unique Cas9 targets in E. coli reveal widespread functionality and rules for gRNA biological design
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librarian
41 views
Combinatorial mutagenesis of N-terminal sequences reveals unexpected and expanded stability determinants of the Escherichia coli N-degron pathway
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librarian
42 views
Peptide Barcodes for miRNA activity assessment in mammalian cells
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librarian
42 views
Integration of strain and process optimization to increase autotrophic growth of engineered Komagataella phaffii
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librarian
43 views
Unveiling the hidden window of prime editing
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librarian
43 views
PYEAST - Python Enabled Automated Strain Transformaiton
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Carol Hartley
43 views
Multiobjective learning and design of bacteriophage specificity
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librarian
44 views
Experimental Evaluation of AI-Driven Protein Design Risks Using Safe Biological Proxies
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Geoffrey Taghon
53 views
Engineered Acinetobacter baylyi ADP1-ISx cells are sensitive DNA biosensors for antibiotic resistance genes and a fungal pathogen of bats
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librarian
45 views
Sequestration-Based Neural Networks That Operate Out of Equilibrium
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librarian
46 views
A Saccharomyces boulardii synthetic biotic platform for delivery of therapeutic nanobodies to ameliorate gastrointestinal inflammation
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librarian
51 views
Efficient CRISPR-Cas9-mediated genome editing of the cane toad (Rhinella marina)
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librarian
46 views
Experimental Evaluation of AI-Driven Protein Design Risks Using Safe Biological Proxies
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librarian
51 views
CRISPRi-Linked Multi-Module Negative Feedback Loops to Address Winner-Take-All Resource Competition
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librarian
50 views
Systematic Mapping of Bacterial CRISPRa Design Rules and Implications for Synergistic Gene Activation
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librarian
48 views
Peptide nucleic acid (PNA) and DNA hybrid three-way junctions and mesojunctions
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Bharath Raj Madhanagopal
46 views
Sustainable production of plastic-degrading enzymes in Chlamydomonas pacifica
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Crisandra Diaz
48 views
Integrating Recombinase-Based Feedback and Feedforward Control for Optimal Resource Decoupling
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librarian
47 views
Multilayered regulation by RNA thermometers enables precise control of Cas9 expression
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librarian
50 views