Synthetic Biology

In vitro evolution of DNA operators enables multivalency protein-DNA interactions: towards programmable transcription factor regulation
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Daiana Capdevila
8 views
A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE AND REPRESSIBLE VECTORS FOR FINE-TUNED GENE EXPRESSION
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librarian
17 views
Optimizing Lentiviral Vector-Based Delivery of SCN1A transgenes to Mammalian Cells
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librarian
14 views
Mitigating Family Effects in RNA Secondary-Structure Prediction with Latent-Space Continual Learning
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librarian
16 views
Generative design of sequence specific DNA binding proteins
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librarian
35 views
Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs)
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librarian
21 views
PhAGE Enables One-Step Genome Integration of Large DNA Fragments in Escherichia coli
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Shingo Nozaki
18 views
yakRNA Design: A semantic multimodal RNA composer
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librarian
19 views
Unsupervised protein language models learn patterns of enzyme function
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librarian
15 views
The Synthetic Epitope Atlas: High-Throughput Design and Validation of De Novo Antibody-Antigen Complexes
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librarian
43 views
A cinnamyl alcohol dehydrogenase scaffold organizes monoterpenoid indole alkaloid biosynthesis
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librarian
37 views
Host background shapes the portability of a non-canonical translation initiation system across Escherichia coli strains
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librarian
28 views
ADAR-Sense: an open-access, species-agnostic web tool for automated, user-customisable ADAR-based RNA sensor design
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librarian
26 views
A Divergent Class of Arylamine N-Acetyltransferases Catalyzes Convergent Amidative Condensation of Polyketides in Manumycins Biosynthesis
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Xudong Kong
29 views
Rhizobacterial Biosensors Spatially Map Natural and Engineered Sucrose Exudation
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librarian
37 views
Application of Engineered NK-92 Cell Extracellular Vesicles in the Treatment of Systemic Lupus Erythematosus
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Xiaowei Dou
34 views
Engineering CAR-Vδ2 T cells to boost persistence and anti-tumor function
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librarian
36 views
Coordinated Membrane Deformation Driven by a Minimal Set of Spiroplasma MreB Isoforms
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librarian
37 views
Systematic CRISPRi screening reveals genetic modulators of  E. coli  isoprenoid production
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Kimberly Reynolds
34 views
In-situ Target Base Editing Combining with Biosensor-driven Strategy Reveals Critical Single Nucleotide Variants for Enhanced Recombinant Protein Secretion in Pichia pastoris
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Chong Zhang
37 views
Existence and Localization of a Limit Cycle in a Class of Benchmark Biomolecular Oscillators
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Sidhanta Mohanty
35 views
Multicenter preclinical validation of next-generation CAR T cells: a strategy for harmonization, reproducibility, and its feasibility in clinical translation
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librarian
32 views
Expression landscape of heterologous enzymes in Synechocystis sp. PCC 6803
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Elias Englund
40 views
Sequence Design and Phylogenetic Inference with Generative Flow Networks
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librarian
42 views
DNA Protonuclei as Programmable Nuclear Mimics Reveal Environmental Context on Protein Phase Separation
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librarian
38 views
Exploring Chromosomal Position Effects for Predictable Tuning of Metabolic Pathways in Yeast
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Chang Dong
35 views
Automated Knowledge Graph Construction for CAR T Cell Receptor Design via Hybrid Text Mining
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Haomiao Luo
44 views
Maximally Divergent Synonymous Gene Design with SIRIUS
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Stefano Lonardi
40 views
Gain-Scheduled Optogenetic Feedback for Disturbance Rejection in Bacterial Batch Cultures
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librarian
40 views